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Figure 5 | BMC Physiology

Figure 5

From: Blood pressures, heart rate and locomotor activity during salt loading and angiotensin II infusion in protease-activated receptor 2 (PAR2) knockout mice

Figure 5

Effects of angiotensin II and saline infusions on PAR 2 -/- versus PAR 2 +/+ hemodynamics and locomotor activity during 12 h light periods. Variables were measured every 30 s for 13 days via radiotelemetry during infusion s.c. with angiotensin II (1 μg/kg/min) or isotonic saline (0.5 μl/h). Symbols represent the change in means of variables averaged over 12 h light periods relative to baseline periods prior to implant of micro-osmotic pumps. Data obtained from 13 PAR2 +/+ saline, 15 PAR2 +/+ Ang II, 7 PAR2 -/- saline and 9 PAR2 -/- Ang II. * P < 0.05, PAR2 -/- Ang II compared to PAR2 +/+ Ang II using 2 way ANOVA and Bonferroni post-hoc. # P < 0.05, Ang II-treated PAR2 +/+ and PAR2 -/- versus saline-treated groups, 2 way ANOVA and Bonferroni post-hoc test.

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